The Significance of NBI-ME on Chronic Gastritis with Intestinal Metaplasia

In order to prevent the occurrence of gastric cancer, it is very important to find early gastric cancer and precancerous lesions timely. This research discussed diagnostic value of methylene blue staining under white light endoscopy, light blue crest (LBC) and white opaque substance (WOS) under NBI-ME on chronic gastritis with intestinal metaplasia. 227 patients who accepted gastroscopy in our hospital and met the inclusion criteria were selected. Olympus GIF-HQ290 electronic gastroscope was applied to finish examination under the common white light mode, to observe whether there was LBC and WOS under the NBI-ME mode and to observe whether there was baby blue staining area under the methylene blue staining. Biopsy mucosae were conducted on the diseased region. Biopsy histopathology was diagnosed as a “golden standard”. Moreover, the relation between special performance and pathology of intestinal metaplasia under three endoscopes was compared. 227 patients were examined, showing that sensitivity, specificity, positive predictive value and negative predictive value of methylene blue were 97.01%, 98.75%, 97.01% and 98.75%, respectively. These of LBC were 80.60%, 97.50%, 93.10% and 92.31%, and these of WOS were 82.09%, 96.88, 91.67% and 92.81%. All of them conducted a chi-square test with pathological results and P>0.05. Three kinds of special performance under the endoscope had higher consistency with pathological results. Three kinds of special performance under the endoscope had higher consistency with pathological results. Methylene blue staining under the gastroscope, LBC under NBI-ME and WOS can be used as a simple and effective method to judge whether there is intestinal metaplasia.